Clemson at Louisville - 2025 Matchup Preview
Clemson logo   Clemson Tigers at Louisville Cardinals  Louisville logo
Friday, November 14th 2025 (7:30 PM EST)
Louisville -1.5 (50.5) (-122)  Open: -6.5 | 60.5
Clemson 20 - Louisville: 19  (ACC)

 
Tigers (7 - 6) (5 - 8 - 0)
Coach Dabo Swinney (180 - 46)
Avg Score : 27 - 21 (30 - 15 on Road)
Record Prediction: 7.4 - 5.6 (#64)
'25 Opponents: (Elite: 0) (Good: 1) (Avg: 1) (Bad: 0)
LOU 2nd straight Home Game
LOU is playing their 5th straight game
Our Line: Louisville -2.5  (SP+ LOU -3)
Projected Score: CLEM: 24 - LOU: 26 (50)
LOU Win prob: 50% | Cover: 47%
CLEM Travel: 293 miles
Cardinals (9 - 4) (4 - 9 - 0)
Coach Jeff Brohm (18 - 8)
Avg Score : 30 - 21 (34 - 19 @ Home)
Record Prediction: 8.5 - 4.5 (#42)
'25 Opponents: (Elite: 0) (Good: 2) (Avg: 1) (Bad: 0)
 
Clemson's 2025 Schedule
DateMatchupSpreadTotalResultO/UCover
Sat 8/30 Clemson vs LSU-3.557.5L 10 - 17UN
Sat 9/6 Clemson vs Troy-31.051.5W 27 - 16UN
Sat 9/13 Clemson at Georgia Tech-2.549.5L 21 - 24UN
Sat 9/20 Clemson vs Syracuse-17.553.5L 21 - 34ON
BYE WEEK
Sat 10/4 Clemson at North Carolina-15.547.5W 38 - 10OY
Sat 10/11 Clemson at Boston College-14.054.5W 41 - 10UY
Sat 10/18 Clemson vs SMU-3.549.5L 24 - 35ON
BYE WEEK
Sat 11/1 Clemson vs Duke-4.555.5L 45 - 46ON
Sat 11/8 Clemson vs Florida State-1.556.5W 24 - 10UY
Fri 11/14 Clemson at Louisville+1.550.5W 20 - 19UY
Sat 11/22 Clemson vs Furman-41.555.5W 45 - 10UN
Sat 11/29 Clemson at South Carolina+2.545.5W 28 - 14UY
Sat 12/27 Clemson vs Penn State-2.547.5L 10 - 22UN

Total: Elite: 0, Good: 5, Avg 2, Bad 3, Poor 1
Played: Elite: 0, Good: 4, Avg 1, Bad 3, Poor 1
Future: Elite: 0, Good: 1, Avg 1, Bad 0, Poor 0
Wins: Elite: 0, Good: 1, Avg: 0, Bad: 3, Poor: 0
Losses: Elite: 0, Good: 3, Avg: 1, Bad: 0, Poor: 1

Predictions for Clemson's Schedule
Louisville's 2025 Schedule
DateMatchupSpreadTotalResultO/UCover
Sat 8/30 Louisville vs Eastern Kentucky-37.557.5W 51 - 17ON
Fri 9/5 Louisville vs James Madison-15.057.0W 28 - 14UN
BYE WEEK
Sat 9/20 Louisville vs Bowling Green-26.550.5W 40 - 17ON
Sat 9/27 Louisville at Pittsburgh-3.053.5W 34 - 27OY
Sat 10/4 Louisville vs Virginia-6.559.5L 27 - 30UN
BYE WEEK
Fri 10/17 Louisville at Miami+10.549.5W 24 - 21UY
Sat 10/25 Louisville vs Boston College-25.554.5W 38 - 24ON
Sat 11/1 Louisville at Virginia Tech-10.552.5W 28 - 16UY
Sat 11/8 Louisville vs California-18.548.5L 26 - 29ON
Fri 11/14 Louisville vs Clemson-1.550.5L 19 - 20UN
Sat 11/22 Louisville at SMU+4.049.5L 6 - 38UN
Sat 11/29 Louisville vs Kentucky-1.045.5W 41 - 0UY
Tue 12/23 Louisville vs Toledo-12.544.5W 27 - 22ON

Total: Elite: 1, Good: 5, Avg 1, Bad 3, Poor 1
Played: Elite: 1, Good: 3, Avg 0, Bad 3, Poor 1
Future: Elite: 0, Good: 2, Avg 1, Bad 0, Poor 0
Wins: Elite: 1, Good: 2, Avg: 0, Bad: 2, Poor: 1
Losses: Elite: 0, Good: 1, Avg: 0, Bad: 1, Poor: 0

Predictions for Louisville's Schedule
Important Stats (2024)
 Teams                  Off Explosive.Off SuccessPPGRush SuccessOL Yds Per AttRush YPGPass SuccessPass YPGOff ScoreZoneDef Explosive.Def SuccessDef PPGRunD SuccessPass D SuccessDef ScoreZonePenalty YPGTO PGDef TO PG
CLEM#21 (.27)47% (24)27.250% (12)3.28 (29)17445% (36)2794.33 (29)#52 (.14)40% (48)20.543% (68)38% (36)3.64 (48)47.60.71.9
LOU#15 (.31)46% (26)29.948% (20)3.09 (56)17345% (30)2514.27 (31)#73 (.18)40% (49)21.240% (44)40% (65)3.98 (87)46.10.81.2
 Teams                  Off Explosive.Off SuccessPPGRush SuccessOL Yds Per AttRush YPGPass SuccessPass YPGOff ScoreZoneDef Explosive.Def SuccessDef PPGRunD SuccessPass D SuccessDef ScoreZonePenalty YPGTO PGDef TO PG
CLEM0%0%000%000%0%0%0000
LOU0%0%000%000%0%0%0000



Overall Stats 2024
 Teams                  GamesPPGPPG H/RSuccess RatePts PerOppTO1stD PGTotalYds PGRushYds PGPassYdsPGRYPARun RatePass RateRun SuccessPass SuccessHavoc RateTotal PPA
CLEM Offense1427.229.646.7%4.330.7244521742795.243%56%50%45%13%.27
LOU Defense1321.218.940.2%3.981.2 - - - - - 49%51%40%40%16%.18
 Teams                  GamesPPGPPG H/RSuccess RatePts PerOppTO1stD PGTotalYds PGRushYds PGPassYdsPGRYPARun RatePass RateRun SuccessPass SuccessHavoc RateTotal PPA
CLEM Defense1420.515.440.1%3.641.9 - - - - - 46%53%43%38%19%.14
LOU Offense1329.933.846.4%4.270.8204241732515.845%54%48%45%13%.31

Additional Stats 2024
 Teams                  GamesPossession Time1st Downs PG3rd Down %4th Down %Penalties PGPenalty Yds PGOff TO PGDef TO PGTFL PGSacks PGD/ST TDsAvg Field Pos
Clemson1430:2923.944%59%4.947.60.71.96.12.5230.1
Louisville1327:3920.140%40%5.946.10.81.25.82.2130.3
Run Game Stats (2025)
 Teams                  GamesRun Play RateRun Play SuccessRush Att PGRush Yds PGRush Yds Per AttRushing TDsRun Pred Pts AddedOL Yds Per Att3rd/4th & ShortFront 7 HavocRun Play Explosivness
CLEM Offense1443% (113)50% (12)33.6173.85.223 (52).24 (19)3.28 (29)72% (78)8% (40)0.96 (69)
LOU Defense1349% (50)40% (44) - - - - .08 (43)2.9 (51)65% (25)11% (43)0.99 (71)
 Teams                  GamesRun Play RateRun Play SuccessRush Att PGRush Yds PGRush Yds Per AttRushing TDsRun Pred Pts AddedOL Yds Per Att3rd/4th & ShortFront 7 HavocRun Play Explosivness
CLEM Defense1446% (20)43% (68) - - - - .15 (84)2.93 (54)59% (8)11% (38)1.12 (119)
LOU Offense1345% (103)48% (20)29.9172.75.827 (30).2 (35)3.09 (56)65% (116)8% (27)1.04 (43)

Pass Game Stats (2025)
 Teams                  GamesPassPlay RatePassPlay SuccessComp PGAtt PGYds PGYds PAYds PCTDs    Ints    PassPlays PPAPassPlays ExplPassDowns RatePassDowns Succ RatePassDowns PPADB HavocPassDowns Expl
CLEM Offense1456% (23)45% (36)23.637.8278.57.411.837 (2)7 (26).33 (38)1.5 (79)30% (39)38% (6).58 (4)5% (21)2.1 (39)
LOU Defense1351% (88)40% (65) - - - - - - 9 (76).27 (87)1.7 (111)31% (78)33% (99).26 (48)5% (94)1.8 (14)
 Teams                  GamesPassPlay RatePassPlay SuccessComp PGAtt PGYds PGYds PAYds PCTDs    Ints    PassPlays PPAPassPlays ExplPassDowns RatePassDowns Succ RatePassDowns PPADB HavocPassDowns Expl
CLEM Defense1453% (114)38% (36) - - - - - - 16 (10).15 (28)1.6 (60)35% (26)32% (90).3 (66)8% (20)2 (64)
LOU Offense1354% (32)45% (30)19.630.9251.58.112.823 (41)6 (10).41 (9)1.7 (34)30% (40)38% (8).5 (9)5% (40)2.1 (42)

Clemson's Power Ratings
Clemson's Power Rating: 14.58  #24
Clemson's Offense Rating: 17.99  #38
Clemson's Defense Rating: 3.41  #16
2025 Talent Rating: 988.00  #12
Blue Chip Ratio: 52%  #12
Clemson's 2025 Expected Record: 7.4 - 5.6
Clemson's 2025 Overall SP+ Rating: 9.5  #34
Clemson's Offense SP+ Rating: 27.5  #65
Clemson's Defense SP+ Rating: 18.9  #24

Average Talent
Average ACC Talent Rating is 852.82
Average Power Five Talent: 877.82
Average FBS Talent: 715.76

Power Ratings Matchup
Clemson: 14.58   Louisville: 14.49

SP+ Ratings Matchup
Clemson: 9.5   Louisville: 12.4




Louisville's Power Ratings
Louisville's Power Rating: 14.49  #36
Louisville's Offense Rating: 17.35  #43
Louisville's Defense Rating: 5.77  #27
2025 Talent Rating: 788.00  #57
Blue Chip Ratio: 7  #46
Louisville's 2025 Expected Record: 8.5 - 4.5
Louisville's 2025 Overall SP+ Rating: 12.4  #25
Louisville's Offense SP+ Rating: 31.6  #39
Louisville's Defense SP+ Rating: 19.8  #29

Average Talent
Average ACC Talent Rating is 852.82
Average Power Five Talent: 877.82
Average FBS Talent: 715.76


Clemson Scoring
Offense: 27.2 PPG
Offense on Road: 29.6
Defense: 20.5 PPG
Defense on Road: 15.4

Clemson's 2025 Record
Record: 7 - 6
Record vs Spread: 5 - 8 - 0
Over/Under Record: 4 - 9
Record on Road: 4 - 1
Record vs Spread on Road: 4 - 1 - 0
Record as Dog vs Spread: 2 - 0 - 0
Record as Road Dog vs Spread: 2 - 0 - 0
Projected Score
Louisville 26
Clemson 24

Projected Total Points: 50
Louisville Scoring
Offense: 29.9 PPG
Offense at Home: 33.8
Defense: 21.2 PPG
Defense at Home: 18.9

Louisville's 2025 Record
Record: 9 - 4
Record vs Spread: 4 - 9 - 0
Over/Under Record: 6 - 7
Record at home: 5 - 3
Record vs Spread at home: 1 - 7 - 0
Record as Fav vs Spread: 3 - 8 - 0
Record as Home Fav vs Spread: 1 - 7 - 0


YearDateHomeScoreAwayScoreSpreadCoverTotalO/U
202511/14Louisville19Clemson20Louisville -1.5Clemson50.5Under
202411/02Clemson21Louisville33Clemson -11Louisville62.5Under
202211/12Clemson31Louisville16Clemson -7Clemson52.0Under
202111/06Louisville24Clemson30Clemson -3.5Clemson46.0Over
201910/19Louisville10Clemson45Clemson -24Clemson62.0Under
201811/03Clemson77Louisville16Clemson -38Clemson61.0Over
201709/16Louisville21Clemson47Clemson -3Clemson61.0Over
201610/01Clemson42Louisville36Clemson -3.5Clemson64.0Over
201509/17Louisville17Clemson20Clemson -5Louisville54.0Under
201410/11Clemson23Louisville17Clemson -6.5Louisville0
TeamWinsCoversO/U
Louisville134 Overs
Clemson975 Unders

WinsCoversFavsDogs
Home Teams4 - 64 - 63 - 31 - 3
Road Teams6 - 46 - 43 - 13 - 3

(#24) CLEM at (#36) LOU
Overall StatsOvr
CategoryCatCLEMLOU
Net PPPPPPNRNR
Power RatePwr #24 #36
SP+SP+ #34 #25
Perf GradeGrade #50 #16
OffenseOff #65 #49
DefenseDef #33 #11
Spec TeamsST #30 #70
TalentTal #12 #57
Blue ChipsBC% #12 #46
Clemson Notes
(11/2) Things are getting toxic with HC Swinney
(11/2) 1-4 at home going into FSU game. Beat Troy
(11/2) Off great, Def torched, ST's cost bad in Duke L
(10/21) Top WR Bryant Wesco out for season (back inj)
(10/19) 5 straight losses at home vs FBS after SMU loss
(10/19) QB Vizzina was good, but Run Off putrid in SMU L
(10/16) QB Klubnik apparently injured, may miss SMU
(9/20) Def torched by Cuse. Klubnik can't carry this Off
(9/18) Get LT Leigh, WR Williams, S Barnes back (Cuse)
(9/15) Off just bad, Klubnick asked to carry too much
(8/30) Run game awful, OL awful. Not an elite team
(6/6) OL returns 5/5, a top 10 unit in all CFB
Clemson Injury Report
Louisville Notes
(11/21) QB Moss is ? for SMU game.
(11/16) Bad L vs Clemson, QB Moss culture comments??
(11/15) 3 losses as home favs in last 6 games
(11/4) RB1 I Brown out weeks, maybe SMU/UK (leg)
(11/1) Sluggish vs VT, Run Off 235 big w/ Moss off night
(10/17) Special teams all around one of the best in CFB
(10/17) Brohm special vs Miami, Run Off enough, Def great
(9/27) 17-0 comeback win at Pitt. Moss good, RBs/OL bad
(9/17) Starting LB S Clark likely out for season (leg)
(9/5) Good battle with JMU, Run Off needs work
(7/28) Def meh LY, added 17 via portal. DL & DB heavy
(7/17) DBs all new, starters come from 8 portals.
Louisville Injury Report
Clemson on Offense
Pass heavy Offense 55%, Run: 43%
CategoryCat
CLEM OffLOU Def
PPPOffPPPNRNR
Perf GradePerf #65 #11
SuccessSuc #24 #49
ExplosiveExp #70 #109
PPAPPA #21 #73
PowerPwr #38 #27
SP+SP+ #65 #29
Pts POPPO #29 #87
HavocHav #25 #62
Clemson Run Game
Pass heavy Offense 55%, Run: 43%
CategoryCat
CLEM OffLOU Def
Run GameRun #105 #41
Run SuccessRSuc #12 #44
Run ExplRExp #69 #71
PPAExp #19 #43
Run BlockR Blk #79 -
OL YdsOLY #29 #51
Stuff RateStuff #53 #22
TackleTak -  #39
Clemson Pass Game
Pass heavy Offense 55%, Run: 43%
CategoryCat
CLEM OffLOU Def
Pass GamePass #29 #20
Pass SuccessPSuc #36 #65
Pass ExplPExl #79 #111
PPAExp #38 #87
Pass Rush/BlockP Blk #73 #3
F7 HavocF7 #40 #43
DB HavocDB #21 #94
Louisville on Offense
Pass heavy Offense 54%, Run: 43%
CategoryCatLOU OffCLEM Def
PPPDefPPPNRNR
Perf GradePerf #49 #33
SuccessSuc #26 #48
ExplosiveExp #14 #106
PPAPPA #15 #52
PowerPwr #43 #16
SP+SP+ #39 #24
Pts POPPO #31 #48
HavocHav #23 #20
Louisville Run Game
Pass heavy Offense 54%, Run: 43%
CategoryCat
LOU OffCLEM Def
Run GameRun #10 #35
Run SuccessRSuc #20 #68
Run ExplRExp #43 #119
PPAExp #35 #84
Run BlockR Blk #66 -
OL YdsOLY #56 #54
Stuff RateStuff #54 #44
TackleTak -  #11
Louisville Pass Game
Pass heavy Offense 54%, Run: 43%
CategoryCatLOU OffCLEM Def
Pass GamePass #83 #62
Pass SuccessPSuc #30 #36
Pass ExplPExl #34 #60
PPAExp #9 #28
Pass Block/RushP Blk #69 #39
F7 HavocF7 #27 #38
DB HavocDB #40 #20
Program Comparison
LOU 5 Year Profile: Consistent Average P4
'25 Profile: Up to Top 25 Contenders

CLEM 5 Year Profile: Consistent Top 25 Contenders
'25 Profile: Down to Average P4

Weather Forecast
Playing in Papa John's Cardinal Stadium
Conditions:
Temp: 0°
Rematch from Week 12
Louisville -1.5 (50.5)
Clemson won at Louisville this year (20-19)

Previous Matchups
Clemson beat Louisville last year (20-19)
Louisville beat Clemson in 2024 (33-21)

  
CLEM's OC Garrett Riley (been OC for 3 years)
Player NameCOMPATTPCTYDSTDINTYPA
Cade Klubnik25739266%29431667.5
Christopher Vizzina457163%406415.7
Player NameCARYDSTDYPCLONG
Adam Randall168814104.846
Gideon Davidson6026004.328
Chris Denson7108115.450
Cade Klubnik839441.113
Player NameRECYDSTDYPCLONG
T.J. Moore52837416.175
Antonio Williams55604411.064
Bryant Wesco Jr.31537617.373
Adam Randall3625437.135

View Clemson's Full Roster

CLEM's DC Tom Allen (in his first season)
Top DefTackTFLSACKSPRESSPD
Sammy Brown10714665
Wade Woodaz707123
Ronan Hanafin642004
Avieon Terrell485308
SacksTackTFLSACKSPRESSPD
Will Heldt (Tr)46156102
Sammy Brown10714665
T.J. Parker379571
Jaheim Lawson197443
Pass DTackTFLSACKSPRESSPD
Avieon Terrell485308
Ashton Hampton453108
Sammy Brown10714665

LOU's OC Brian Brohm (been OC for 3 years)
Player NameCOMPATTPCTYDSTDINTYPA
Miller Moss (Tr)24438064%26791677.1
Deuce Adams152171%112005.3
Player NameCARYDSTDYPCLONG
Isaac Brown10188478.878
Keyjuan Brown9670467.367
Braxton Jennings3720015.422
Shaun Boykins3719015.126
Player NameRECYDSTDYPCLONG
Chris Bell72917612.764
Caullin Lacy60635210.648
Dacari Collins (Tr)13219116.836
Jaleel Skinner2120429.733

View Louisville's Full Roster

LOU's DC Ron English (been DC for 3 years)
Top DefTackTFLSACKSPRESSPD
TJ Quinn958314
D'Angelo Hutchinson843025
JoJo Evans (Tr)643134
Clev Lubin (Tr)5913873
SacksTackTFLSACKSPRESSPD
Clev Lubin (Tr)5913873
Wesley Bailey (Tr)397650
Adonijah Green316440
TJ Quinn958314
Pass DTackTFLSACKSPRESSPD
D'Angelo Hutchinson843025
Rene Konga295225
Tayon Holloway424104